Found 11 matching trials
Safety, Tolerability, and Efficacy Study of CLL442 in Patients With Cutaneous Squamous Cell Carcinoma in Situ (SCCis)
PHASE1The purpose of this first in human and proof of concept study is to charact...
Location
Novartis Investigative Site
Re-administration of Intramuscular AAV9 in Patients With Late-Onset Pompe Disease
PHASE1A recombinant AAV vector has been generated to carry the codon-optimized ac...
Location
Clinical and Translational Research Building (CTRB), University of Florida
Daily Topical Rapamycin for Vitiligo
PHASE2In current Dermatology practice, options for vitiligo remain limited. The p...
Status
Active Not Recruiting
Location
Medical University of South Carolina
Topical Rapamycin/Sirolimus for Complicated Vascular Anomalies and Other Susceptible Lesions
PHASE1Proposed Study: Treatment protocol for the use of the topical Rapamycin/Sir...
Location
Nemours Children's Health, Jacksonville
Tuberous Sclerosis Complex: Facial Angiofibroma Skin Cream
PHASE1The objective of this study is to evaluate the safety and efficacy of a 0.1...
Location
LeBonheur Children's Hospital
Topical Sirolimus in Chemoprevention of Facial Squamous Cell Carcinomas in Solid Organ Transplant Recipients (SiroSkin)
PHASE301.21 SiroSkin is a phase 3, double-blind, multi-centre, parallel-arm, rand...
Status
Active Not Recruiting
Location
Royal Prince Alfred Hospital
Topical Rapamycin to Erase Angiofibromas in TSC
PHASE2The study is a multi-center prospective, randomized, double-blind, placebo-...
Location
University of Alabama at Birmingham
Sirolimus as Secondary Therapy in Chronic Graft-Versus-Host Disease Not Responding To Prior Treatment
PHASE2This phase II trial studies the side effects and how well sirolimus works a...
Location
Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium
Dose-Ranging Efficacy and Safety Study of Topical Rapamycin Cream for Facial Angiofibroma Associated With Tuberous Sclerosis Complex
PHASE2The study aims to compare the safety and efficacy of two different strength...
Location
Phoenix Children's Hospital
Topical Sirolimus for the Treatment of Pachyonychia Congenita (PC)
PHASE1A study to evaluate safety and efficacy of topical sirolimus to treat plant...
Location
Stanford University